Rejuran – the revolution in skin regeneration. A comprehensive guide for professionals

What is Rejuran? Scientific background and mechanism of action

Polynucleotides – the foundation of regeneration

Rejuran is a line of products based on polynucleotides (PN), which are fragments of DNA. Their source is usually Pacific salmon – a biocompatible material, extremely similar to human DNA.

Polynucleotides:

• stimulate fibroblasts to produce collagen and elastin,
• increase angiogenesis, i.e. the formation of new blood vessels,
• act anti-inflammatory, reducing oxidative stress,
• improve skin density and elasticity,
• accelerate repair processes after damage, e.g. scars or pigmentation.

Why is Rejuran so effective?

Unlike traditional fillers or products based solely on hyaluronic acid, Rejuran not only hydrates and fills the skin but also truly rebuilds it. The mechanism of action is biological and long-lasting.

Rejuranhttps://cosmetix.eu/en/producers/rejuran-1678365790.html

Types of Rejuran products – tailored to patient needs

Rejuran is not a single product but a whole line of specialized solutions. Each addresses different skin problems and finds use in specific areas.

1. Rejuran Healer

• The most well-known product in the Rejuran family.
• Focused on overall skin regeneration.
• Indications: loss of firmness, fine wrinkles, improvement of skin quality and elasticity.

Rejuran Healer

2. Rejuran S

• Dedicated to acne scars and atrophic scars.
• Characterized by higher viscosity, which allows it to fill structural skin defects.

Rejuran S

3. Rejuran I

• Designed specifically for the delicate eye area.
• Reduces dark circles, wrinkles, and skin laxity.
• An alternative or complement to hyaluronic acid treatments.

4. Rejuran HB

• A combination of polynucleotides with hyaluronic acid.
• Particularly recommended for severely dehydrated skin.
• Ideal for patients with visible loss of glow and dryness.

5. Rejuran Tone-Up

• Created to improve skin tone.
• Indications: pigmentation, uneven tone, dull complexion.

Biological mechanisms – why is Rejuran unique?

• Biocompatibility – no risk of allergic reactions thanks to the biological compatibility of polynucleotides.
• DNA-level regeneration – protection against oxidative damage.
• Fibroblast stimulation – increased production of collagen type I and III.
• Anti-inflammatory effect – reduction of inflammatory markers in the skin.

Clinical effects – backed by studies

Clinical studies show that after a series of 3–4 Rejuran treatments:

• skin elasticity improves by 15–20%,
• fine wrinkles are reduced by 25–30%,
• skin hydration increases by 20%,
• acne scars are visibly reduced.

Patients and doctors emphasize the natural look of the results – no artificial filling, while skin quality visibly improves.

Clinical applications of Rejuran

• Face – rejuvenation, wrinkle reduction, skin quality improvement.
• Eye area – dark circles, wrinkles, laxity.
• Neck and décolleté – revitalization and skin tightening.
• Acne scars – filling and regeneration.
• Dehydrated and damaged skin – intensive hydration and repair.

The Rejuran treatment process

1. Topical anesthesia – lidocaine cream.
2. Product administration – mesotherapy injection technique (microdeposits).
3. Frequency – usually 3–4 treatments every 3–4 weeks.
4. Combination therapy – excellent results when combined with botox, lasers, or hyaluronic acid.

Safety and effectiveness

• Minimal risk of allergic reactions.
• Mild redness and swelling disappear within 1–2 days.
• Effects last up to 12–18 months.

Comparison of Rejuran with other biostimulators

Who is Rejuran for?

• Patients aged 25+ with first signs of aging.
• People with acne scars.
• Patients with thin, dehydrated skin.
• Those seeking natural regeneration instead of artificial filling.

Contraindications: pregnancy, breastfeeding, autoimmune diseases, skin infections.

FAQ – frequently asked questions from patients

Is the treatment painful?
Minimally, thanks to anesthesia.

When are the effects visible?
First effects after 2 weeks, full results after 2–3 months.

How many treatments are needed?
Standard: 3–4 in a series.

Can I combine Rejuran with botox?
Yes – it produces synergistic results.

Conclusion

Rejuran is currently one of the most innovative and effective biostimulators available in aesthetic medicine. Thanks to the unique polynucleotide technology, it ensures deep skin regeneration, natural effects, and long-lasting results.

👉 Explore all available Rejuran products at Cosmetix.eu and choose the solution tailored to your patients’ needs.